Evaluation of Clinical and Laboratory Findings and Diagnostic Difficulties in Children with Vitamin B12 Deficiency

نویسندگان

چکیده

Aim: In this study, we evaluated the clinical and laboratory data of healthy children with vitamin B12 deficiency. The benefits methylmalonic acid (MMA) homocysteine levels difficulties encountered in diagnosing deficiency were pointed out. 
 Materials Methods: A total 70 whose serum cobalamin below 126.5 pg/ml included study. age, gender, B12, urine MMA, plasma homocysteine, white blood cell, hemoglobin, thrombocyte, main corpuscular volume (MCV), platelet (MPV), folic acid, ferritin obtained retrospectively from hospital’s medical records. correlation analysis test compared MMA homocysteine.
 Results: mean age was 8.21±6.15 years, found 6.29% children. Cobalamin ranged 50-126 pg/ml, a 102.57±18.97 pg/ml. Urine 0.59±0.67 ng/ml 13.50±0.67 g/dl, respectively. coefficient value (r) to be -0.342 -0.437, moderately negative for normal 36 patients, 48 patients. Conclusions: Vitamin is common micronutrient diagnosis can complex who do not display typical findings, particularly elevated homocysteine.

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ژورنال

عنوان ژورنال: Pediatric practice and research

سال: 2022

ISSN: ['2147-6470']

DOI: https://doi.org/10.21765/pprjournal.1053277